Synthetic Fermentation Heatmap

What is this?

This is a heatmap showing the outcome of 40,000 chemical reactions using a 3-component coupling called Synthetic Fermentation. See our paper for more details.

How-To

Each square in this heatmap is an aggregate over all terminators used with the specified initiator (y-axis) and monomer (x-axis). Click a heatmap square to see all products with different terminators making up that square. You will see the structures of the desired products, the background color indicates which product type (A, B, C, None) was actually obtained as the major product. Empty (white, or black in dark mode) squares indicate that no attempt was made to use this reactant combination.

Legend

Major ProductABCNone of theseR1NHOR2R3SNNR4R1NHOR2R3SNHNR4CO2HR1NHN+R2SNR4R3CO2-
M1M2M3M4M5M6M7M8M9M10M11M12M13M14M15M16M17M18M19M20M21M22M23M24M25M26M27M28M29M30M31M32M33M34M35M36M37M38M39M40M41M42M43M44M45M46M47M48M49M50M51M52M53M54M55M56M57M58M59M60M61M62M63M64M65M66M67M68M69M70I1I2I3I4I5I6I7I8I9I10I11I12I13I14I15I16I17I18I19I20I21I22I23I24I25I26I27I28I29I30I31I32I33I34I35I36I37I38I39I40I41I42I43I44I45I46I47I48I49I50I51I52I53I54I55I56I57I58I59I60I61I62I63I64I65I66

Click a square to see the products!